Study: Usage of IGRAs Could Decrease Over diagnosis of the Latent Tuberculosis Infection


According to a stud, the use of interferon gamma release assays (IGRAs) can possibly decrease overdiagnosis of the latent tuberculosis infection in the people coming from the countries that has been using the bacilli Calmette-Guerin vaccine and they also have moderate to the high rates of disease.

Christine Ho, epidemiologist at US CDC said, the Tuberculosis Epidemiologic Studies Consortium (TBESC) of the US CDC has convened an expert panel of the researchers of tuberculosis (TB) along with the public health officials for the purpose of reviewing the research gaps in the treatment and diagnosis of the latent TB infection and the US CDC has also recommended a research goal for the consortium.

Christine Ho said, the study panel has concluded that, the assessment of the tuberculin skin test (TST) which was compared with the interferon gamma release assays (IGRAs) is going to be providing an important information on how the will be performing the main populations in the United States, and she also said, the results from this assessment can possibly be used across the globe for the purpose of improving the treatment to prevent the tuberculosis disease along with providing better programs of public health.

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Christine Ho, along with her colleagues has also performed an observational study, along with enrolling the participants, which are having high risk for the latent TB infection or progression to the TB disease at around 10 sites across the United States along with 18 affiliated clinics in the country.